Diagnosis of C. difficile-associated diarrhea in immunosuppressed patients
نویسندگان
چکیده
منابع مشابه
Clostridium difficile-associated diarrhea.
At our hospital, the number of cases of Clostridium difficile-associated diarrhoea increased from 29 in 1993 to 210 in 1995. The case notes of 110 patients with C difficile-associated diarrhoea during the first 6 months of 1995 were analysed retrospectively. The majority of the patients (106) had received antibiotics before the onset of diarrhoea; 46 had received three or more different antibio...
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clostridium difficile is a frequently identified cause of nosocomial gastrointestinal disease. it has been proved to be a causative agent in antibiotic-associated diarrhea, antibiotic-associated colitis, and pseudomembraneous colitis. this study was aimed to determine the prevalence of c.difficile- associated diarrhea in hospitalized patients with nosocomial diarrhea. the 942 hospitalized patie...
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Sir—We read with interest the article by Pépin et al. [1], which reports that use of quinolones is a major risk factor for illness during an outbreak of Clostridium difficile–associated diarrhea (CDAD). These results confirm previous observations that quinolones and other antibiotics, such as third-generation cephalosporins, macrolides, broad-spectrumb-lactams, and aminoglycosides, are importan...
متن کاملClostridium difficile-associated diarrhea in adults.
Clostridium difficile is the most important cause of nosocomial diarrhea in adults. Illness may range from mild watery diarrhea to life-threatening colitis. An antecedent disruption of the normal colonic flora followed by exposure to a toxigenic strain of C. difficile are necessary first steps in the pathogenesis of disease. Diagnosis is based primarily on the detection of C. difficile toxin A ...
متن کاملAntimicrobial therapy of Clostridium difficile-associated diarrhea.
Clostridium difficile-associated diarrhea (CDAD) is the most common etiologically-defined cause of hospital-acquired diarrhea. Caused by the toxins of certain strains of C difficile, CDAD represents a growing concern, with epidemic outbreaks in some hospitals where very aggressive and difficult-to-treat strains have recently been found. Incidence of CDAD varies ordinarily between 1 to 10 in eve...
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ژورنال
عنوان ژورنال: Nature Reviews Gastroenterology & Hepatology
سال: 2009
ISSN: 1759-5045,1759-5053
DOI: 10.1038/nrgastro.2009.25